Joanna Mikulska, Anita Bryńska

Zaburzenie obsesyjno-kompulsyjne — metody leczenia i czynniki determinujące ich skuteczność                 55

Obsessive-compulsive disorder — methods of treatment and the factors influencing their efficacy 55

Summary:

The aim of this review is to summarize the known factors which can determine the efficacy of therapy (pharmacotherapy and cognitive-behavioural therapy) in OCD. The Medline and Psych.Info (1966-2003) were reviewed with key words: OCD and CBT, OCD and BT. The emerging data suggest that there exist some factors which can influence the efficacy of therapy in OCD: metabolism of fluorodeoxyglucose in the left orbitofrontal cortex, the clinical picture of the disease - predominance of obsessions or compulsions, predominance of a specific group of symptoms (i.e. sexual/religious obsessions, compulsive hoarding and saving), associated symptoms of depression, duration of illness, the number of previous therapies, the level of functioning before treatment, Y-BOCS score before treatment, compliance with the therapist during the first week of psychotherapy and reduction of anxiety between sessions (two last factors refer to cognitive-behavioural therapy).